#Infected synovial fluid color free#

Diagnostic accuracy of the synovial fluid alpha-Defensin lateral flow test in Periprosthetic joint infection: a meta-analysis. Diagnostic utility of a novel point-of-care test of calprotectin for Periprosthetic joint infection after Total knee arthroplasty: a prospective cohort study. C-reactive protein promotes the activation of fibroblast-like Synoviocytes from patients with rheumatoid arthritis. Serum and synovial fluid levels of serum amyloid A protein and C-reactive protein in inflammatory and noninflammatory arthritis. Elevated levels of fibrinogen-derived endogenous citrullinated peptides in synovial fluid of rheumatoid arthritis patients. Joint fluid, in clinical methods: the history, physical, and laboratory examinations. Fibrin degradation in the synovial fluid of rheumatoid arthritis patients: a model for extravascular fibrinolysis.

Fibrin promotion and lysis in arthritic joints. Permeability of rheumatoid and normal human synovium to specific plasma proteins. A systems biology approach to synovial joint lubrication in health, injury, and disease. The biology of lubricin: near frictionless joint motion. Altered joint tribology in osteoarthritis: reduced lubricin synthesis due to the inflammatory process. Safety and efficacy of US-approved viscosupplements for knee osteoarthritis: a systematic review and meta-analysis of randomized, saline-controlled trials. Viscosupplementation for the treatment of osteoarthritis. Molecular size-dependent specificity of hyaluronan on functional properties, morphology and matrix composition of mammary cancer cells. Recent advances and prospects of hyaluronan as a multifunctional therapeutic system. An analysis of clinical studies of the use of crosslinked hyaluronan, hylan, in the treatment of osteoarthritis. 21-23 September, Canterbury, United Kingdom. Second international meeting on synovium. Does hyaluronan have a role in endothelial cell proliferation of the synovium? Semin Arthritis Rheum. High-molar-mass hyaluronan behavior during testing its radical scavenging capacity in organic and aqueous media: effects of the presence of manganese(II) ions.

#Infected synovial fluid color free#

The reactivity of various free radicals with hyaluronic acid: steady-state and pulse radiolysis studies.

Graff's textbook of urinalysis and body fluids. Composition of joint fluid in patients undergoing total knee replacement and revision arthroplasty: correlation with flow properties. Hyaluronan and synovial joint: function, distribution and healing.

SF is composed of blood plasma ultrafiltrate including some proteins and additional molecules secreted by synovium cells including the lubricant molecules hyaluronan (HA) and proteoglycan 4 (also known as lubricin), cytokines, and metabolic byproducts. Synovial fluid also provides important metabolic support to the avascular joint cartilage and both permits and modulates synovial inflammation (Hui, Wiley Interdiscip Rev Syst Biol Med 4:15–37, 2012). A main function of SF is to lubricate cartilage, allowing for low-friction and low-wear movement of the joint. Synovial fluid (SF) is normally a clear, straw-colored, viscous liquid, with a volume of approximately 1 ml in the normal human knee joint (Hui, Wiley Interdiscip Rev Syst Biol Med 4:15–37, 2012). Changes in color, clarity, viscosity, and shifts in the composition of synovial fluid can provide insight and important clinical information on health and disease of the joint. Competency in synovial fluid analysis is paramount in distinguishing septic from aseptic inflammatory and non-inflammatory arthritis. Breakdown of one or all of these components can lead to degeneration, infection, autoimmunity, and crystalline arthropathies. The biochemical composition of synovial fluid is made up of lubricants, proteins, and small molecules working synergistically to protect the joint from impact, friction, and disease.